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San Francisco 49ers’ Christian McCaffrey (23) runs against the Tennessee Titans in the fourth quarter at Levi's Stadium in Santa Clara, Calif., on Sunday, Dec. 14, 2025. (Nhat V. Meyer/Bay Area News Group)It's a must-win game for the 49ers on the road to capturing the NFC West crown and No. 1 seed in the playoffs. They may be without star tight end George Kittle and receiver Ricky Pearsall, who are battling injuries.
Originally published at Pueng Vongs